Blood pressure is the force behind the flow of blood in the circulatory system. High blood pressure can be very dangerous and in most cases presents no symptoms. It can occur for a number of reasons and causes a variety of more complicated cardiovascular problems. In October of 2010 a study published in the Federation of American Societies for Experimental Biology (FASEB) provides hope for patients having a difficult time controlling their blood pressure.
The P450 Protein
The notion that the P450 protein may be beneficial in cardiovascular medical conditions was simply an idea on a list of possibilities to begin the first phase of testing. The test was done on two groups of mice. The first group was injected with the protein and the other was the control group. The protein worked in the mice by inhibiting the genes in the body that control the inflammation of blood vessel walls. The result was that the blood vessels relaxed and blood pressure was reduced.
The second part of the test was how beneficial it would be in situations that usually increase blood pressure. The mice were put through several physical tests and exposed the mice to various substances that are known to increase blood pressure. The group injected with the P450 protein has lower blood pressure and less kidney damage than the control group. This study illustrates that the injection of this protein cannot only reduce those with a high resting blood pressure but also be beneficial for patients who have a specific trigger to their blood pressure spikes.
Controlling blood pressure levels in the body will not only aid patients with hypertension but may also decrease the risk for other medical conditions. According to The American Heart Associated Americans have high blood pressure for their first stroke (77%), their first heart attack (69%), and those in congestive heart failure (74%).
There are many factors that contribute to high blood pressure. Some of these factors can be controlled such as diet and exercise but others be a result of genetics. High blood pressure is often referred to as the ‘silent killer’ because it presents relatively no symptoms. It is a symptom of many different medical conditions but you don’t know how severe or chronic the condition is until you see a physician.
This study is still in initial phases and will move to human trials. This protein would be beneficial to patients with high blood pressure or patients who want to hedge their bets when they have high blood pressure running in their family. The protein does not appear to be harmful if the patient does not already have high blood pressure and as such it would be beneficial to take not only as a treatment but also as a preventative measure. Perhaps after testing and production have begun it will become a recommended daily medication such as a vitamin or supplement.
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The American Heart Associated