Genetic disorders are commonly well understood among families who pass malformed genes from generation to generation. In cases of recessive genes, it is possible your child could develop complications associated with a genetic disorder for which you may have no prior familial knowledge.
If you are the parent of a toddler, and if you notice changes in your child’s physical development, it is important to consider how recessive genes may play a role in the possible development of Morquio syndrome. Unlike condition such as Phantom Vibration syndrome in children, the symptoms of Morquio syndrome are often not realized until a change in height and weight is recognized by a physician or parent.
For many children born with the recessive genetic defect of Morquio syndrome, the immediate health impact is realized in the days and weeks after birth as there is often a complication associated with normal heart development. In some cases, however, the heart development may be normal and your toddler may not exhibit complications until age two or three years when changes in bone structure and physical development occur.
In toddlers who are adversely affected by Morquio syndrome, the complications may arise as an abrupt stop in growth and development often with a toddler exhibiting complications that seem to mimic dwarfism. If you find, therefore, that your child’s growth has suddenly stopped, it may be prudent to ask about referral to a genetic specialist to determine if recessive genetic complication may be to blame.
If your child is diagnosed with Morquio syndrome, it will be important to find not only a specialist in pediatric care of the physical stature and growth of your child, but also to find a cardiologist who understands the potential heart complication that will arise as well as a metabolic specialist who can provide guidance in managing your child’s metabolic complications as well. While there is no cure for Morquio syndrome, there are steps you can take to manage the potential health risks and work to mitigate long term complications.
For children diagnosed with Morquio syndrome, there can be a direct link between this recessive genetic disorder and the shortened life span. But, with proper diagnosis and treatment early in life, your child’s health can be preserved as long as possible and resolve the acute health issues as they arise.
Sources: Lysosomal Storage Disorders, by Gregory Pastores