Week 2 was a big one for quarterbacks, with at least six signal-callers throwing three touchdown passes.
It was also a big week for young running backs.
Detroit rookie Jahvid Best, second-year Philadelphia Eagles RB LeSean McCoy and fourth-year Atlanta Falcons back Jason Snelling scored three touchdowns each. during Week 2.
Week 2 Fantasy Football Leaders
Matt Schaub, QB, Houston Texans
Schaub bounced back from a quiet opening week by going 38-for-52 for 497 yards and three touchdowns with one interception, five sacks and two rushing yards.
Jahvid Best, RB, Detroit Lions
Best rushed for 78 yards and two scores, and also caught nine passes for 154 yards and a touchdown.
Jay Cutler, QB, Chicago Bears
Cutler was an efficient 21-for-29 for 277 yards and three touchdowns with one sack and three rushing yards.
Jason Snelling, RB, Atlanta Falcons
Snelling got the call when both Michael Turner and Jerious Norwood went down with injuries and carried 24 times for 129 yards and two touchdowns, and caught five passes for 57 yards and another TD.
Peyton Manning, QB, Indianapolis Colts
Manning had another big week, completing 20-of-26 passes for 255 yards and three touchdowns. He was sacked once and finished with minus-three rushing yards.
Aaron Rodgers, QB, Green Bay Packers
Rodgers was 19-for-29 for 22 yards and two touchdowns with no sacks and no intereptions, and he rushed for 20 yards and another TD.
Mark Sanchez, QB, New York Jets
Sanchez was solid in Week 2, going 21-for-30 for 220 yards and three touchdowns. He also had a two-point conversion, was sacked three times and finished with two rushing yards.
LeSean McCoy, RB, Philadelphia Eagles
McCoy busted out in a big way for Philly, rushing for 120 yards and three touchdowns, and catching four passes for eight yards.
Matt Ryan, QB, Atlanta Falcons
Ryan was 21-for-32 for 225 yards and three touchdowns. He was sacked once, fumbled once and rushed for six yards.
Philip Rivers, QB, San Diego Chargers
Rivers went 22-for-29 for 334 yards and three TDs. He was intercepted twice and sacked once.
Drew Brees, QB, New Orleans Saints
Brees went 28-for-38 for 254 yards and two touchdowns on Monday night. He was sacked twice, and also caught a pass for seven yards.
Kyle Orton, QB, Denver Broncos
Orton was 25-for-35 for 307 yards and two TDs. He was sacked once and finished with minus-five rushing yards.
Frank Gore, RB, San Francisco 49ers
Gore tallied 112 yards and a touchdown on the ground, and caught seven passes for 56 yards and another TD. He also fumbled once.