The episode opens as Leonard (Johnny Galecki) looks around at his group of friends in the comic book store and realizes that he is the only one who doesn’t currently have a woman in his life. Leonard becomes sad and a bit frustrated when he comes to the realization that the desperate Howard (Simon Helberg) even has a girlfriend. The most interesting relationship is between Sheldon (Jim Parsons) and Amy Farrah Fowler (Mayim Bialik) because they are perfectly happy with their non-relationship. This situation quickly changes as Amy asks Sheldon if he would be willing to meet her mother.
Confused about Amy’s request Sheldon chases after Leonard looking for clarification about the state of their relationship. Leonard is more than happy to offer the suggestion that Amy clearly wants more out of their relationship. This sends Sheldon into a panic as he tries to avoid all contact with Amy, even going as far as dressing up in a disguise to exit his apartment building.
Leonard finally reaches his breaking point and requests the help of his friend Howard to ask his girlfriend Bernadette (Melissa Rauch) to set him up on a blind date. After Howard and Bernadette work out the details the three arrive at a nice restaurant waiting for Leonard’s date to arrive. What walks through the door seems to surprise everyone as Leonard’s date arrives straight from the gym in her workout clothes. Within minutes it is clear that the two of them don’t share any of the same interests and his date is a bit obnoxious. When Leonard and Howard are alone during the restroom break Leonard tells Howard that he is not interested in his blind date. His tune changes a bit when Leonard’s date returns and asks Leonard if he would like to attend a wedding the following week with the potential that he will get some action. After a brief pause Leonard realizes that one more date might not be so bad if he could get a little companionship.
Meanwhile Amy Farrah Fowler confronts Sheldon and clarifies that his meeting her mother is just a ruse and not an advancement in their relationship. After Sheldon returns to his relationship comfort zone he agrees to play along with the ruse and the two of them set up a very funny video chat with Amy’s mother where they discuss how they are going to have intercourse.
The Desperation Emanation is episode number five in season number four of The Big Bang Theory. Due to a recent horse riding accident Penny (Kaley Cuoco) was unable to perform in this episode. This is definitely an episode worth seeing as there are many great situational comedy moments.