Overview of Collagen
Collagen was introduced in the late 1980s as an instant treatment for wrinkles that could quickly and safely be injected into human skin. However, collagen had its disadvantages. Not only was it expensive and only lasted several months, it also presented risks to the immune system. Today, there are many types of wrinkle fillers used by plastic surgeons to eliminate facial lines. Here you will find the most popular.
Wrinkle Filler Types
There are four basic types of wrinkle fillers used today. These include hyaluronic acid-based fillers (Perlane, Restylane, Evevess, Juvaderm), calcium hydroxlyapatite fillers (Radiesse), human and animal-based collagen (Comoplast, Cosmodern, Artefil), and general fillers, such as Silicone and Sculptra.
Perlane: Perlane is intended for injection into deep layers of skin. It is FDA approved to eliminate mild to moderate wrinkles and lines around the mouth. Perlane lasts about eight to twelve months.
Restylane: Restylane was approved by the FDA in 2003 and is generally used around the mouth. It helps to restore the loss hyaluronic acid that we lose naturally as we age. Restylane is a popular treatment as results are immediate and there is minimal down-time.
Elevess: Elevess contains a high amount of hyaluronic acid fillers that makes it durable and able to treat moderate liens and folds around the nose and cheeks. It also contains Iidocaine in the injection which is a local anesthetic to ease the sting.
Juvaderm: Juvaderm is FDA approved to fix fine lines for cosmetic purposes. Juvaderm Ultra Plus was also created for deeper wrinkles. Each of these treatments last eight and twelve months on average.
Radiesse: Radiesse is a water-based gel which contains hydroxylapatite that is naturally compatible with bioidentical substances in the human body. Radiesse can not be used for fine lines or in the lips as its white color shows through thin layers of skin.
Cosmoplast/Cosmoderm: Comoplast and cosmoderm are both created from FDA approved purified human-based collagen. Mixed with a local anesthetic, these fillers are less painful then other fillers and work great for fine lines around the lips and eyes.
Artefil: Artefil is derived from a bovine collagen which is reabsorbed into the body, resulting in permanent results. However, Artefil is more expensive then the other types of wrinkle fillers.
Silicone: Silicone is not approved by the FDA as it’s believed to be prone to defects. Ophthalmologists commonly use silicone as a treatment for eye disease.
Sculptra: Sculptra is created from a poly-L-latic acid and is approved by the FDA for medical use. It’s not designed to be used for wrinkles, but to add volume to sunken eyes, hollow cheeks, and some facial folds.
There are many different alternatives to collagen that can be injected into the skin by plastic surgeons. Each have their advantages and disadvantages but give individuals an option rather than collagen for the treatment of wrinkles and fine lines.
Injectables and Skin Fillers